Connecting Germs to Diseases

	Connecting Germs to Diseases Although Pasteur proved that some microorganism causes disease, but could not relate or identify an organism to a disease. Robert Koch, a doctor from East Prussia, was the first one to isolate microbes, culture, and attributed the role of a microorganism in a disease, in the year of 1870. Following his discovery of Anthrax in cattle's, Pasture discovered the temperature sensitivity of Anthrax. Pasteur showed that the animals at their normal body temperature (42⁰ C) did not acquire anthrax, but did contract the disease when body temperature dropped around 37 ⁰C. In 1885, Pasteur made his ground breaking discovery, by introducing the concept of immunization. Pasteur was able to raise a vaccine against rabies. The denatured vaccine extracted from the injected animals, protected other animals from Rabies. He save a life of boy, name Joseph Meister, who was the first person in the history to receive any kind of immunizations. Below show the bottle where the tissue materials were dried and vaccine was prepared.
	Touch Me
	Pasteur convinced his physician colleagues that they can be the source of spreading infection through unwashed hands, cloths and surgical tools. He offered the concept of heat sterilization to the physicians and surgeons that became a mandatory rule.

Pasture and Roux realized that active agents migrated from the bite-area to the spinal cord and brain, At this point they were not aware of any specific rabies microorganism. They found that if the extracts of spinal cord and brain from rabid-animals to the healthy animals, the symptoms for rabies appeared within few days.

They wanted to prevent this migration. They archived their goals, by air-drying the spinal cord materials from the diseased animals, in a Roux bottle, over a period of 12 days. The spinal cord was hung from the top of the bottle, as shown in the picture, the air entered through the cotton plug and passed over the drying agent.